Sodium Citrate
- Product Name: Sodium Citrate
- Chemical Name (IUPAC): Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
- CAS No.: 68-04-2
- Chemical Formula: Na3C6H5O7
- Form/Physical State: Granules/Powder
- Factroy Site: Lingwu, Yinchuan, Ningxia, China
- Price Inquiry: sales2@liwei-chem.com
- Manufacturer: Anhui Liwei Chemical Co.,Limited
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- Sodium Citrate is a sodium salt in granular or powder form, commonly used in food processing, where precise pH control is required.
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HS Code |
673064 |
| Chemical Name | Sodium Citrate |
| Chemical Formula | Na3C6H5O7 |
| Molar Mass | 258.07 g/mol |
| Appearance | white crystalline powder |
| Odor | odorless |
| Solubility In Water | very soluble |
| Ph | 7.5–9.0 (5% solution) |
| Melting Point | 300 °C (decomposes) |
| Taste | saline, mildly tart |
| Main Uses | buffering agent, food additive, anticoagulant |
| Cas Number | 68-04-2 |
| Density | 1.7 g/cm³ |
| Stability | stable under normal conditions |
| Storage Conditions | store in a cool, dry place |
| E Number | E331 |
As an accredited Sodium Citrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Sodium Citrate, 500g, packaged in a sealed, white HDPE plastic bottle with a blue screw cap and clear labeling for safety. |
| Container Loading (20′ FCL) | 20′ FCL container can load approximately 25 metric tons of Sodium Citrate, packed in 25kg or 50kg bags on pallets. |
| Shipping | Sodium Citrate is shipped as a non-hazardous, stable chemical, typically in sealed bags, drums, or containers to prevent moisture absorption. Packages must be clearly labeled and stored in a cool, dry area during transport. It is not subject to strict hazardous materials regulations, but standard safety practices should be followed. |
| Storage | Sodium citrate should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from heat and moisture. Keep it away from incompatible substances such as strong acids. Ensure the storage area is free from sources of ignition and protected from physical damage. Proper labeling is necessary, and storage should comply with relevant safety regulations. |
| Shelf Life | Sodium citrate typically has a shelf life of 2-3 years when stored in a cool, dry, and well-sealed container. |
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Our sodium citrate products play a critical role in industrial sectors, providing functional benefits that support compliance, enhance process efficiency, and deliver consistent performance in each use. As manufacturers, we ensure our sodium citrate meets stringent quality and regulatory benchmarks, allowing for precise integration in downstream applications. The following scenarios illustrate key industrial uses, highlighting regulatory standards, formulation ratios, integration points, and end product categories. Sodium citrate is widely used in large-scale food and beverage production lines as a buffering agent and emulsification aid, especially for processed cheese, carbonated beverages, and ready-to-serve sauces. Its controlled addition regulates acidity, improves melt properties of cheese, and stabilizes beverage pH, which supports batch consistency and shelf stability. Food producers add sodium citrate during blending or cooking stages where uniform distribution is necessary for quality assurance, with real-time pH monitoring guiding the precise formulation. Industry compliance standards
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2. Pharmaceutical Manufacturing: pH Adjustment in Injectable PreparationsIn commercial pharmaceutical plants, sodium citrate acts as a buffering salt to control pH in injectable formulations, particularly for blood anticoagulant solutions, vitamin C injections, and specialized IV electrolyte infusions. It is weighed and dissolved in WFI (Water for Injection) with validated equipment, and precisely monitored by HPLC or potentiometric titration to ensure stringent USP, Ph. Eur., or ChP standards, minimizing risks of batch deviations or regulatory nonconformance in finished vial or ampoule products. Industry compliance standards
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3. Detergents and Cleaners: Water Softening and pH ControlMajor producers of household and institutional cleaning agents utilize sodium citrate to sequester calcium and magnesium ions, ensuring cleaner rinse and minimizing scale buildup in automatic dishwashing and laundry operations. Detailed formulation targets optimize the citrate input to balance cleaning efficiency, product stability, and regulatory phosphate limits, particularly where regional standards restrict other chelates. The material is metered into concentrated base blends or dry powder mixing systems using gravimetric or loss-in-weight feeders. Industry compliance standards
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4. Industrial Water Treatment: Corrosion Inhibition and Scale ControlWater treatment system manufacturers rely on sodium citrate as a biodegradable chelating agent for scale and corrosion control in closed-loop cooling systems, boiler water, and high-purity industrial rinsing lines. Operators control dosing with real-time titration based on feedwater mineral content, thereby optimizing inhibitor efficiency and regulatory discharge compliance. Ongoing QC documents incoming sodium citrate batch certificates, tracked against ISO management systems and site-specific corrosion monitoring protocols. Industry compliance standards
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5. Cosmetics and Personal Care: pH Regulation and ChelationWithin the cosmetics sector, formulators employ sodium citrate to stabilize pH, prevent metal ion-catalyzed oxidation, and enhance preservative efficacy in a range of water-based personal care products, including creams, gels, and cleansing wipes. Its integration occurs during the aqueous phase compounding, with pH titrated to meet skin compatibility and shelf-life targets as defined by product-specific standards. Product development teams coordinate real-time QC checks to confirm compliant citrate dosing and batch traceability in GMP production environments. Industry compliance standards
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6. Laboratory Diagnostics: Blood Collection and Anticoagulant SolutionsDiagnostic reagent manufacturers use sodium citrate to prepare anticoagulant solutions for blood collection, supporting accurate coagulation testing in clinical laboratory workflows. It is blended with ultra-pure water and subjected to rigorous endotoxin and sterility tests before final packaging in evacuated blood collection tubes. Automated production lines monitor each step under ISO 13485 and CLIA requirements, ensuring traceable lot release and consistent reagent performance across hospital and commercial laboratory networks. Industry compliance standards
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Competitive Sodium Citrate prices that fit your budget—flexible terms and customized quotes for every order.
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- Sodium Citrate is manufactured under an ISO 9001 quality system and complies with relevant regulatory requirements.
- COA, SDS/MSDS, and related certificates are available upon request. For certificate requests or inquiries, contact: sales2@liwei-chem.com.
Sodium Citrate: A Closer Look from the Manufacturer’s Perspective
Understanding Sodium Citrate and Its Place in Daily Production
Every batch of sodium citrate that leaves our factory marks a milestone in our ongoing commitment to practical chemistry and real-world usability. In the daily rhythm of our operation, sodium citrate stands out for its flexibility and reliability. Produced mainly as Trisodium Citrate Dihydrate, with a fine powder appearance and a pleasant, mild taste, it has proven itself as an ingredient that performs under many conditions without losing its character. Each particle, though simple by nature, carries an importance in precise pH adjustment and consistent chelation that supports process stability in food, pharmaceuticals, and industial cleaning.
Manufacturing sodium citrate starts with quality raw materials, fresh citric acid and high-purity sodium carbonate, under careful heat control to avoid degradation. Our staff constantly monitors reaction conditions—temperature, mixing speed, and pH—so the material forms evenly and maintains a high solubility. The finished product arrives in clean, white crystalline powder, both anhydrous and dihydrate, each meeting different storage and performance needs. Water content forms the key difference: the dihydrate variety handles smoothly and dissolves rapidly in both hot and cold water, a factor especially valuable in high-output automated systems.
Why Production Quality Matters in Sodium Citrate
Every kilogram we produce reflects a balance between chemical precision and process efficiency. If the pH slips or raw material quality falters, downstream users feel it in the handling, the taste, or even dissolution rates. Dairy processors, for example, comment on the way sodium citrate keeps melting cheese smooth and stretchable, rather than letting it turn grainy or oily. Beverage formulators choose our powder for reliable sour-salt notes without muddying flavors or causing cloudiness. Unwanted caking or trace impurities risk costly downtimes in automated feeders, so we pay attention to drying times and particle size control.
A batch can look perfect under a microscope, yet fail if chloride or sulphate levels creep above strict guidelines. These trace elements might seem minor, but in practical use—especially in injectable pharmaceuticals—they affect patient safety and manufacturing compliance. We dedicate resources to detection and removal, using deionized water and filters rated for the tightest particle sizes. Even subtle changes, like a switch of supplier for soda ash, force us to validate and revalidate every step. Our technicians know they aren't just meeting a lab spec—end-users depend on the confidence that each shipment will work like the last.
The Role of Sodium Citrate Across Industries
Walking through the blending area, the diversity of applications always impresses. Food processors order sodium citrate in bulk for its role as an emulsifier and pH buffer. It lets bakers dial in the right acid balance for leavening, keeps mayonnaise shelf-stable without harsh preservatives, and gives jams a dependable set. Each use has different drivers: some need the clean tartness, others require control over crystal formation, and still more value it's salt substitute qualities.
Pharmaceutical clients often set the highest bar, specifying exact microbiological standards. Their usage goes beyond flavor masking—sodium citrate acts as a key stabilizer for blood and plasma, where it prevents clotting without promoting excess sodium intake. Allergen protection ranks high. By maintaining tight control over incoming citric acid, we assure customers they receive material free of peanut or wheat cross-contaminants. Solubility checks and impurity screenings form a daily routine; one missed detail leaves us open to costly recall or, worse, patient harm.
Water treatment engineers prefer sodium citrate for systems where residue or scaling pose risk. The chelating strength of citrate ions extracts calcium and magnesium, reducing fouling and extending equipment life in cooling towers and reverse osmosis units. Unlike EDTA or phosphates, sodium citrate biodegrades quickly and sidesteps regulatory challenges around wastewater disposal. Operators tell us they see fewer scale build-ups, lower chemical footprints, and smoother compliance reporting. That feedback directs our decisions on refining crystal size distributions for ready dosing.
In cleaning and household products, sodium citrate gives detergents an edge without introducing harsh or persistent chemicals. It softens water, boosts the efficiency of surfactants, and sidesteps conflicting regulations faced by phosphate-based chelators. Formulators appreciate the predictable performance, especially where label claims about mildness and minimal environmental impact matter. We field requests to fine-tune particle size, moisture content, and flowability, recognizing how much a small adjustment can matter in high-speed mixing or spray-drying.
What Sets Sodium Citrate Apart from Other Salts and Buffers?
Comparing sodium citrate with other buffering or chelating salts reveals distinct advantages that arise less from theory than from years on loading docks and production floors. As a buffer, sodium citrate covers a pH range especially suited to food, beverages, and medical solutions—where you want a controlled sour but not the stomach-upsetting sharpness of pure acid or the flat taste of a straight salt. It's less aggressive than sodium phosphate, which can push pH above what yeast, bacteria, or even flavor systems tolerate.
Another distinction emerges in how sodium citrate interacts with metal ions. In process or beverage plants with old piping, iron or copper leaches easily. Citrate binds stray metals tightly, reducing impacts on flavor, process wear, and product discoloration. It doesn't strip essential nutrients or create disposal headaches associated with more persistent chelators like EDTA. In biochemistry and pharmaceutical labs, this translates to fewer side reactions and greater stability in diagnostic kits.
Our customers often draw parallels with pure sodium chloride, the most familiar food additive. Sodium citrate delivers similar functional value but with lower sodium, an advantage for manufacturers designing "low-salt" recipes without losing taste or preservative power. Its pleasant tartness elevates health-focused products, where formulators want to avoid aggressive flavors. In baking and processed foods, sodium citrate enables finer adjustment of acidity than most other sodium salts, opening doors for recipes that must strike a balance between flavor, shelf life, and structure.
Industrial users sometimes compare sodium citrate with more conventional builders like polyphosphates. They notice reductions in corrosion and less scaling on expensive machinery. Additionally, the environmental profile of sodium citrate stands in sharp contrast to more persistent alternatives. It breaks down through ordinary wastewater treatment, keeping downstream loads light and reducing both discharge fees and complaints from local regulators. Our conversations with municipal plant operators confirm that this trait is increasingly important as regulation tightens worldwide.
Model, Specifications, and Physical Features
On our packing line, sodium citrate typically exits the process as a fine, white crystalline powder—sometimes requested as a coarser granule for improved flow in high-speed feeding. Popular models include Trisodium Citrate Dihydrate, with purity exceeding 99% and very low limits on iron, arsenic, and heavy metals. For specialty niches like hemodialysis or injectable drugs, request volumes smaller but the purity demanded climbs even higher, often to parts per billion for contaminants. Each drum, sack, or bulk hopper tracks by lot number, making sure if a specification issue appears downstream, we can trace it right back to the source tank or even a specific hour of production.
Moisture content can't be overlooked—our dihydrate holds water naturally, with a stability that fits food production best. The anhydrous variety, preferred in some lab or dry-blending settings, brings longer shelf-life and resists caking in low-humidity climates. Each form offers similar solubility profiles, but some dissolves faster, a detail that matters when production speed counts. Crystal structure affects not just how quickly the product dissolves, but whether it dusts or compacts during mixing, conveying, or packing.
Particle size remains adjustable, within constraints, to fit automated dosing systems, powder blends, or direct consumer packaging. Customers developing effervescent tablets, drink powders, or rapid-dissolving supplements rely on particle sizes as small as 60-120 mesh. Conversely, bulk chelation systems in water treatment facilities opt for larger uniform granules, which minimize bridging and clogging. We supply technical datasheets with each load, but real-world performance feedback from mixers, blenders, and other operator-level staff ends up shaping specification tweaks more than anything dictated from the lab.
Our perspective has always aligned with transparency and support for independent verification. All outgoing sodium citrate bears third-party lab certifications, compliant with applicable compendia, including the latest revisions of FCC, USP, and E number requirements in Europe. We run in-house checks on microbiological loads, heavy metals, loss on drying, and pH range. But only feedback from customer lines confirms whether real stability and uniform blending hold during scale-up.
The Human Element in Sodium Citrate Production
Clean machinery and precision lab numbers mean little without people committed to each step. The team behind sodium citrate understands how quickly a tiny handling issue—like a leaking valve or dust from open hoppers—can compromise purity. Our operators have caught product deviations before automation would have flagged a warning, simply from experience on taste, texture, or even how a shovel glides through the powder. They know the potential impact: a delayed shipment may mean a cheese plant stalls production, or a pharmaceutical firm faces an audit after a failed batch.
After years of refining our process, we've learned to invest in skilled hands and clear communication. Every morning, before machines rumble to life, technicians debrief on supplier updates and equipment behavior. If a drum of citric acid shows slight discoloration, the lot doesn’t enter the system until cleared. If QC sees an outlier on moisture content, no debate over margins—out it goes. Our approach might sometimes slow releases, but downstream effects of shortcuts or missed contaminants run wide and deep.
Customers appreciate candid conversations more than marketing gloss. We offer real-time shipment tracking for larger contracts, and open channels for production visits or audits. The expectation isn’t perfection, but responsiveness—catching changes before they drift into bigger problems. We’re honest about challenges, too; climate-driven raw material shortages, or rising energy costs, put pressure on maintaining standards. Over years, we’ve developed backup supply chains, forward stocks of critical reagents, and greater self-sufficiency for handling waste water or side-streams. Our aim is to carry the risk ourselves, not offload it downstream.
Sodium Citrate in a Changing Regulatory Landscape
Recent shifts in global regulation challenge every producer to think ahead. Some countries pursue stronger limits on residual heavy metals, while others focus on allergen control, GMOs, or cross-contamination with animal products. Our response involves both investment and process vigilance. We’ve upgraded filtration and air control in production, expanded allergen screenings, and partnered with accredited testing labs. Standards like REACH, FCC, and ISO give us a baseline, but we never consider a product truly compliant unless it meets the most restrictive client specifications. That means active engagement with evolving regulations—monitoring or even anticipating changes before they appear in customer contracts.
Sodium citrate falls into regulation sets for both food and pharma, meaning we don’t get to pick one quality system. We cross-train teams in allergen management, recall protocols, and transportation requirements. Tracing an issue—be it from an imported raw material or a contamination incident—calls for not just batch records but detailed cleaning logs, operator notes, and third-party certifications. Over time, this level of documentation pays back with trust. Clients know that should a deviation occur—by us or a supplier—we have the detail to act, not just react.
Environmental compliance adds another layer. Sodium citrate’s biodegradability gives us a strong starting point compared to many synthetic chelators, but that only holds if upstream and downstream controls remain strong. Consumer demand for “clean label” ingredients pushes us to keep lowering impurity loads, while municipal water officials want assurance of safe breakdown. We work with regulators to monitor effluent, demonstrate neutralization steps, and adapt process flows to minimize waste. As government oversight grows stricter on all fronts, the requirements keep evolving; our focus remains on staying ahead, not playing catchup.
Solutions to Challenges in Sodium Citrate Production and Supply
Consistent product quality depends on cooperative relationships, not just in-house technology. Reliable sodium citrate starts with raw materials. We audit citric acid and soda ash producers, checking not only chemical specs but also plant hygiene, tracking, and ethical practices. Real traceability means we can identify not just which container yielded a batch, but which mine or orchard produced the original material. That level of detail helps us intervene early if weather, logistics, or labor unrest threaten supply.
Energy costs and emissions factor into production planning. Modern sodium citrate plants recycle heat from reactor vessels to preheat next batches or vaporize waste streams. By laying out our process lines for minimal transfer distance, and updating control software regularly, we keep our operational footprint small. This isn’t only about compliance—downstream firms, especially those with robust CSR goals, increasingly choose suppliers who prove tangible environmental progress.
Customer demands drive regular upgrades on packing lines and IT systems. Food producers want tamperproof bags with batch-level tracking and QR codes to authenticate shipments. Pharma clients expect double-sealed drums, full chain-of-custody, and digital delivery of COAs before containers are received. Meeting these needs means steady reinvestment—new filling machines, better barcode tracking, cloud-based inventory systems. Complaints, when they arise, go straight to continuous improvement teams, who investigate root causes and roll out fixes plant-wide.
Workforce retention, often overlooked, sits at the core of reliable supply. Sodium citrate’s purity depends on vigilant eyes and hands. By offering professional development, safety bonuses, and clear communication, we keep turnover low and manufacturing insight high. New hires undergo not only technical but also ethical training—why skipping a sample or releasing a questionable batch endangers far more than a line manager’s reputation. Our pride in product runs deep, and turnover statistics reflect it.
Industry-Driven Developments in Sodium Citrate Formulation
As consumer trends and industrial needs evolve, sodium citrate’s formulation sees periodic reexamination. Health-driven customers, responding to medical research linking high sodium intake to various diseases, look for new blends. We have developed sodium citrate variants with potassium or calcium substituting for some sodium, providing similar buffering characteristics with less sodium per dose. This involves changes not just in recipe, but in how we monitor crystallization, manage solubility, and package the end product. Some adaptation arises from regulatory drivers updating sodium-per-serving limits in food and beverage.
Growth in plant-based and vegan markets has sparked more inquiry into the origins and processing aids used during sodium citrate’s production. Removing all animal-based processing components came early in our timeline, but full confirmation now extends to cleaning agents, anti-dust coatings, even lubricants in packing. Auditable standards for “vegan” classification reach into transport and repacking; while some may call it excessive, the demand exists and enough buyers request it to warrant formal tracking.
Interest in “clean label” formulations further shapes our direction. While sodium citrate remains synthetic by processing, it is derived from fermentation of natural sugars. Transparency on this, both in sourcing and conversion, helps downstream users justify label claims. We see growing requests for documentation on non-GMO sourcing, allergen absence, and compliance with evolving “natural” additives guidelines. While perfection isn’t always practical, openness brings buyers along as partners in the journey.
Long-Term Outlook for Sodium Citrate Manufacturing
The world rarely stands still, and standing still in sodium citrate manufacturing means falling behind. Longer-term, we foresee more sophisticated expectations—tighter purity, clearer traceability, faster response times, and more collaborative development of product variants. This puts us in continual conversation with R&D labs, regulatory agencies, and grassroots users. Experience shows problems, whether raw material disruptions or regulatory shifts, rarely solve themselves. Our responsibility as a manufacturer exists in the day-to-day, in how we maintain discipline from receiving dock to final shipping seal.
Sodium citrate continues to reflect the larger arc of modern manufacturing: attention to quality, trust in skilled hands, willingness to adapt, and respect for end users. We remember that every batch will connect someone in a lab, a bakery, a hospital, or a cleaning lineup—and that performance, purity, and practical reliability create value beyond any spreadsheet or marketing claim. Each day in production gives us another chance to earn that trust, and to improve the product for everyone relying on it—customers, collaborators, and communities alike.
