Lycopene

    • Product Name: Lycopene
    • Chemical Name (IUPAC): 2,6,10,14,19,23,27,31-Octamethyldotriaconta-2,4,6,8,10,12,14,16,18,20,22,24,26,30-tetradecaene
    • CAS No.: 502-65-8
    • Chemical Formula: C40H56
    • Form/Physical State: Powder
    • Factroy Site: Lingwu, Yinchuan, Ningxia, China
    • Price Inquiry: sales2@liwei-chem.com
    • Manufacturer: Anhui Liwei Chemical Co.,Limited
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    Specifications

    HS Code

    738460

    Name Lycopene
    Chemical Formula C40H56
    Molecular Weight 536.87 g/mol
    Appearance Red crystalline solid
    Solubility Insoluble in water, soluble in organic solvents
    Natural Sources Tomatoes, watermelon, pink grapefruit, guava, papaya
    Cas Number 502-65-8
    E Number E160d
    Melting Point 172°C
    Category Carotenoid pigment
    Usage Dietary supplement, food coloring
    Stability Sensitive to light, heat, and oxygen
    Taste Odorless, tasteless
    Storage Conditions Store in a cool, dark, dry place
    Bioavailability Enhanced when consumed with fat

    As an accredited Lycopene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Lycopene, 10g, packaged in a sealed amber glass bottle with clear labeling for chemical identity, purity, safety, and storage instructions.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for Lycopene: Packed in airtight, food-grade barrels or cartons, securely palletized for safe, stable international shipping.
    Shipping Lycopene should be shipped in tightly sealed, light-resistant containers to prevent degradation. It should be kept cool and dry, ideally at temperatures below 25°C. For bulk quantities, use food-grade or chemical-resistant drums. Ensure proper labeling and comply with local transport regulations, as lycopene is non-hazardous but sensitive to light and heat.
    Storage Lycopene should be stored in a tightly sealed, light-resistant container to prevent degradation from light and oxygen. It should be kept in a cool, dry place, ideally under inert gas (such as nitrogen or argon) to minimize oxidation. Refrigeration at 2–8°C is recommended for long-term storage. Avoid exposure to heat, moisture, and direct sunlight to preserve its stability and potency.
    Shelf Life Lycopene typically has a shelf life of 2-3 years when stored in airtight containers, protected from light, heat, and moisture.
    Application of Lycopene

    Applications of Lycopene in Industrial Manufacturing

    Lycopene, a carotenoid compound sourced primarily from tomatoes, finds widespread and critical downstream application in several tightly regulated industrial sectors. Our manufacturing protocols focus on purity, concentration control, and comprehensive documentation to meet stringent industry requirements. Below are major application scenarios where our lycopene is deployed by professional downstream manufacturers, each with a distinct process profile and product output.

    1. Nutritional Supplements

    Leading dietary supplement producers incorporate lycopene as an antioxidant component, specifically in softgel capsules and multivitamin tablets targeting cardiovascular and cellular health markets. Manufacturers must source lycopene in highly concentrated, standardizable forms to enable accurate product labeling and regulatory claim substantiation. They carefully adjust dosage to fit local health authority guidelines, factoring in bioavailability enhancement techniques such as oil suspension or beadlet encapsulation during formulation. The downstream workflow integrates lycopene after the initial blending stage, moving directly to encapsulation or tabletting, where environmental controls prevent isomerization and degradation.

    Industry compliance standards

    • United States Pharmacopeia (USP) monographs for dietary ingredients
    • European Food Safety Authority (EFSA) health claims guidelines
    • Good Manufacturing Practice (GMP) for nutritional products (21 CFR Part 111/ISO 22000)
    • Chinese Pharmacopoeia (ChP) standards for nutraceutical content

    Typical usage ratio

    • 5–20 mg per serving; usually 0.03–0.2% by weight in capsule or tablet mass, based on national recommended dietary intake and formulation design

    Downstream process integration

    • Oil suspension preparation or micronization, then added during premix blending; final incorporation before encapsulation or tableting under controlled temperature and light conditions

    Final product types

    • Softgel capsules, hard-shell capsules, multivitamin tablets, single-ingredient lycopene supplements

    2. Functional Foods & Beverages

    In fortified juice, dairy, and bakery sectors, formulators aim to enrich consumer-ready products with stable natural color as well as antioxidant attributes. Here, lycopene must maintain pigment integrity through pasteurization, shear mixing, and pH changes. Food technologists select either water-dispersible or oil-dispersible forms, integrating them at specific process stages to optimize retention and uniformity. Incorporation follows distinct protocols, typically at the batching or emulsification stage, with strict allergen and cross-contaminant risk management.

    Industry compliance standards

    • Codex Alimentarius food additive provisions (INS 160d)
    • EU Regulation (EC) No 1333/2008 on food additives
    • FDA generally recognized as safe (GRAS) notice for lycopene from natural sources
    • FSSC 22000 food safety management certification

    Typical usage ratio

    • 10–50 mg/kg in beverages; 3–15 mg/kg in bakery items; ratios vary with color intensity target and regional maximum allowed additive level

    Downstream process integration

    • Direct addition to liquid matrix during homogenization or to dough/batter during mixing; for dairy, incorporated before pasteurization or fermentation steps

    Final product types

    • Fortified juices, dairy drinks, yoghurts, energy bars, fortified breads, functional confectionery

    3. Pharmaceutical Preparations

    Pharmaceutical companies utilize lycopene as a botanical active ingredient for finished dosage forms such as capsules or oral suspensions, seeking proven antioxidant and adjunctive properties in licensed prescription or OTC products. Strict source control, traceability, and consistency in assay are mandatory, and process chemists must validate extract purity in compliance with pharmacopeial specifications. Lycopene is usually introduced during the final blending stage of the drug product, with downstream steps including granulation, drying, and precision dosing to ensure each batch meets label claim and stability requirements.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) lycopene monographs
    • WHO Good Manufacturing Practices for pharmaceutical products
    • USFDA Drug Master File (DMF) certificate for pharmaceutical-grade lycopene
    • Indian Pharmacopoeia Standards for plant-based actives

    Typical usage ratio

    • 5–15 mg per unit dose; adjusted by clinical indication and country-specific maximum limits

    Downstream process integration

    • Introduced during active ingredient blending after granulation; dosage accuracy is monitored in real-time per QA protocols prior to filling and sealing

    Final product types

    • Prescription antioxidant capsules, oral suspensions, combination multivitamin pharmaceuticals

    4. Cosmetics & Personal Care

    Major skincare and cosmeceutical producers leverage lycopene for its antioxidant stability against environmental stressors, often in anti-aging creams, serums, and sun care products. The supply specification targets low-residue, high-purity dispersion for formulation into both oil-based and water-based systems. Downstream formulators incorporate lycopene either during the oil phase of emulsion-making or post-emulsification for gels to preserve actives. Manufacturing follows strict allergen, heavy metals, and microbiological contamination checks, with critical control during milling or dispersion to ensure homogeneity in finished goods.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009
    • Cosmetic Ingredient Review (CIR) Expert Panel safety assessment
    • China GB 7916 Hygiene Standards for Cosmetic Ingredients
    • ISO 22716 Cosmetics Good Manufacturing Practices

    Typical usage ratio

    • 0.01–0.05% by weight in creams or serums, depending on functional claims and stability trials

    Downstream process integration

    • Added to the heated oil or lipid phase during emulsification for creams/lotions; for gels or serums, incorporated post-emulsification under ambient or cooled conditions to minimize degradation

    Final product types

    • Anti-aging creams, skin brightening lotions, high-SPF sun care, antioxidant serums, face masks

    5. Animal Nutrition & Feed

    Lycopene plays a role in specialty animal feed, primarily in pet food and aquaculture where enhanced pigmentation and antioxidant support are desired for health claims and product differentiation. Feed formulators select stable, encapsulated lycopene variants explicitly tested for uniform distribution in pellets or meal. Dosing depends on animal species and intended functional benefit, with careful monitoring to avoid over-supplementation. Integration occurs during the micronutrient premix phase, followed by mixing and extrusion or pelleting, with subsequent heat stability testing on the final feed batch.

    Industry compliance standards

    • Association of American Feed Control Officials (AAFCO) ingredient regulations
    • EU Regulation (EC) No 1831/2003 on feed additives
    • GMP+ Feed Safety Assurance (FSA) certification
    • China Feed Additive Standards GB/T 1886.326

    Typical usage ratio

    • 5–30 mg/kg in complete feed; precise dosage determined by feed formulation software based on target species and pigmentation requirements

    Downstream process integration

    • Blended into vitamin-mineral premix, then combined with base feed ingredients before extrusion or pelleting; post-process stability analyzed on retained samples

    Final product types

    • Premium aquafeed pellets, pet food kibbles, fortified livestock feed, ornamental fish flakes

    Free Quote

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    Certification & Compliance
    More Introduction

    Lycopene: Our Experience with This Valuable Pigment

    Understanding Lycopene and What Sets It Apart

    Growing and producing lycopene puts us in direct contact with its vivid color, natural origins, and versatile functionality every day. From the moment we start with healthy tomatoes, we see how lycopene can shape the end product—whether it's meant for foods, dietary supplements, or cosmetic preparations. Lycopene shows up as a brilliant red pigment, belonging to the carotenoid family, signaling ripeness and freshness in fruits like tomatoes, watermelons, and pink grapefruits. That color isn't just visually appealing; it means the presence of a powerful antioxidant that draws consistent scientific attention.

    As a manufacturer, our offering covers lycopene in several forms: water-dispersible powder, oil suspensions, and crystalline extracts. Each batch comes directly from controlled extraction protocols, ensuring high purity—commonly exceeding 96% for crystalline lycopene. Our standard grade runs at 10% lycopene content in powder forms, with higher concentrations available for specific needs. We focus sharply on batch-to-batch reliability, driven by HPLC and UV-Vis confirmation, meeting the expectations of food, nutraceutical, and cosmetic industries.

    Direct Applications in Industry

    Lycopene gives manufacturers a plant-based color for beverages, confectionery, processed foods, and bakery products. The vividness and stability of its red hue appeals to formulators who want to reduce or replace artificial dyes. Nutraceutical firms choose lycopene not just for color but also for antioxidant marketing value, supporting eye, skin, and cardiovascular health claims. Even in the cosmetic sector, lycopene works as an ingredient for creams and lotions thanks to studies around skin protection from oxidative stress.

    Some food companies have switched to lycopene because it offers heat stability in processing—even at pasteurization or baking temperatures, its color holds up better than many other carotenoids. The oil-soluble nature simplifies incorporation into lipid matrices like margarine, salad dressings, and fortified oils. We see this advantage in the bakery sector, where clients opt for lycopene powder in instant mixes, gaining vibrant color intensity. Beverage manufacturers favor our water-dispersible powders because they disperse with minimal sediment, crucial for clear drinks and juices.

    Safety, Purity, and Traceability

    Maintaining stringent sourcing and processing parameters is non-negotiable for us. We use non-GMO tomato varieties, following strict protocols from seed to harvest. Our extraction avoids aggressive solvents, relying primarily on food-grade ethanol and supercritical CO2 technology. The crude extract moves through successive filtration, purification, and crystallization steps before final concentration. Each stage keeps lycopene’s structure intact, with regular sampling across the cycle to ensure no residual pesticides or contaminants.

    Quality assurance teams run extensive checks for heavy metals, microbiological purity, and pesticide residues. Finished powders and oils pass through third-party labs on top of regular in-house testing using validated methodologies. Modern HPLC analysis confirms lycopene concentration to within 0.2% of declared values, so end users know exactly what they’re putting in their products. Our traceability system tracks every batch to its source farm and extraction lot, which remains available for audit at any step along the supply chain.

    Meeting regulatory standards forms the spine of our quality management. EU and US food safety standards require robust documentation and transparency, so we maintain full recall capability and standardized digital records. Our lycopene products have GRAS status in both food and dietary uses, and comply fully with EC No 1333/2008 and other global directives. Our team prepares documentation for Kosher, Halal, and vegetarian labeling, working closely with clients across diverse cultural environments.

    How Our Offering Differs From Synthetic Lycopene

    Plenty of lycopene on the global market is synthesized from petrochemical precursors. While that can lower cost, we focus our manufacturing solely on natural lycopene extracted from plant sources, mostly tomatoes. The process is more resource-intensive, but the outcome matters for product labeling and marketing claims. Many customers and end users prefer “naturally sourced” on packaging, and some regions require clear distinction between botanical and synthetic sources.

    Natural lycopene contains small amounts of other tomato carotenoids, such as phytoene and phytofluene, which sometimes contribute to the overall antioxidant profile. These minor components may give a more “complete” antioxidant effect compared to lab-made, single-ingredient lycopene, though some studies yield mixed results. We encourage transparency about these differences in technical data sheets, so clients can make informed choices based on cost, function, and market preference.

    Our production skips the use of toluene or other aromatic hydrocarbons often used in some synthetic processes. This aligns well with clean-label trends and retail requirements in both high-end and mass-market supermarket chains. Over years of dialogue with brand owners and regulatory staff, we’ve seen a steady shift toward tomato-derived lycopene—even in regions where lower-cost synthetic options remain legal.

    Our Perspective on Lycopene’s Health Value

    Much of lycopene’s demand comes from research linking its antioxidant action to positive health outcomes. Peer-reviewed evidence shows lycopene neutralizes free radicals, particularly singlet oxygen, protecting tissues from oxidative damage. Population studies report lower rates of cardiovascular disease among groups with higher dietary lycopene intake, especially from tomatoes. Some clinical trials have looked at lycopene supplementation for prostate health, skin photo-protection, and metabolic wellness, though differences in formulation and dosage affect results.

    We pay close attention to scientific developments because customers often request data to back up label claims. The European Food Safety Authority, FDA, and other authorities judge health claims based on rigorous review, not marketing brochures. Though a “clinically proven” label carries weight, no single dietary compound solves public health issues. Still, the consensus supports lycopene’s valuable role as one part of a balanced diet and a safe, naturally occurring food ingredient. We aim for realism—providing technical details and studies where possible, without promising miracle cures.

    We also get direct feedback from supplement formulators about lycopene’s bioavailability challenges. Lycopene in its raw crystalline form absorbs less efficiently than lycopene embedded in emulsions or natural food matrices. Some partners request oil-based lycopene to boost uptake in softgels, while others add micelle-forming agents for powder-based applications. As a manufacturer, we tailor particle size, carrier oil choice, and vitamin E blending based on the customer’s finished dosage form. That practical flexibility became essential as more supplement brands sought differentiation—often in large, competitive markets.

    Decades of Practical Manufacturing Experience

    Experience has shown that controlling the earliest steps in raw material selection, crop handling, and extraction leads to fewer quality issues later. Tomatoes pick up environmental variation from year to year—weather, soil quality, and even local pest pressure can swing pigment yield by as much as 15%. We work directly with partner farms, scheduling harvest only at full ripeness when lycopene concentration peaks in the tomato’s pericarp. Our staff oversees shipment to the extraction site the same day, avoiding heat and spoilage that degrade pigment levels.

    Extraction crews handle each load by the hour, not the day, washing out impurities and prepping for solventless extraction. Quality managers sample every incoming batch for color, moisture, and pesticide residues. We continually invest in staff training, safety measures, and automation systems to catch problems early, maintaining stable output even through seasonal fluctuations. That experience translates into lower rejection rates and more consistent lycopene concentration, which customers value, especially for dosage-sensitive products.

    From extraction onward, each processing line follows strict controls. Pressure vessels, separators, rotary evaporators, and filtration systems get cleaned and sanitized between runs, calibrated on a maintenance schedule that has held up under external audits. Technicians document the outcome at each batch checkpoint, capturing the details in electronic logs. Finished lycopene then spends at least 72 hours in quality quarantine, released only after all assays pass. These are not just compliance steps—they’re the foundation for long-term relationships with downstream users.

    Optimizing for Textures and Dispersion

    Physical form and dispersibility play a crucial role in final product performance. Lycopene’s oil-soluble nature means simply grinding it into flour or water-based beverages does not give the intended effect. We create micronized powders using carrier agents that improve suspension in aqueous matrices. This keeps lycopene from settling out or clumping in instant drink powders, protein shakes, and crystalline beverage mixes.

    For oil-based applications, we supply lycopene pre-dispersed in vegetable oils such as sunflower or MCT oil. This ensures homogenous distribution in salad dressings, margarines, and supplementation oil blends. We’ve picked up on nuances—for example, powder mesh size, surfactant pairing, or oil type affecting shelf life and dose accuracy. Our R&D group runs stability trials with client-provided food bases to ensure real-world viability, not just lab numbers.

    We field questions from experienced formulators and new product developers alike: how to minimize pigment loss during baking, storage, or high-shear processing; which form best resists color fade in ready-to-drink beverages; what works for press-tab and encapsulation methods. Our technical team answers those with direct data, application trials, or by developing new blend systems when existing products can’t manage the latest processing demand.

    Environmental Impact and Sustainable Production

    Manufacturing at commercial scale involves choices about sustainability. We work from a standpoint of using only non-GMO, responsibly grown tomatoes, prioritizing contracts with farms that meet modern traceability standards. Byproducts from our extraction—pomace, skins, and seeds—move into animal feed or compost streams, lowering our waste footprint. Water management matters especially in regions where irrigation competes with urban demand. Our sites operate on closed-loop water recovery systems, reducing total water demand per ton by over 40% in the past five years.

    Reducing solvent use, recycling extraction medium, and switching to energy-efficient process heaters all make an impact at full industrial scale. We compare our environmental data yearly and share sustainability updates with clients—the largest buyers often set audited targets for lifecycle assessments. Receiving feedback from sustainability officers and brand managers helps us focus on improvements that matter, not just on-paper certifications. We participate in traceability pilots for future EU supply chain law compliance, as well as ongoing staff training on environmental stewardship and reporting.

    Tackling Challenges in Lycopene Manufacturing

    Every production year brings its own mix of challenges. Raw tomato prices spike with poor harvests in key growing regions. Climate volatility means careful planning for backup sourcing and logistical reroutes. Scaling up extraction without diluting quality requires constant vigilance—scaling too quickly can lead to under-extracted lots, pigment loss, and costly rework. Shipping delays or new regulatory checks test even seasoned logistics professionals; delays risk quality declines for sensitive products that cannot wait weeks in hot or humid storage.

    Response means keeping technical staff open to process changes and cultivating good upstream partnerships with growers and transporters. Our managers run stress tests on logistics and in-house stockpiles before peak production starts. Regular dialogue with regulatory officials helps avoid surprises during routine or new export clearances. Our experience has taught that real-time monitoring, thorough documentation, and willingness to adapt smaller batch runs all contribute to overcoming these short-term hurdles.

    Future Directions and Research

    Upcoming research in lycopene points toward more uses in novel food applications and hybrid nutraceutical blends. Scientists are exploring microencapsulation for even better bioavailability, as well as combination products with plant sterols, omega-3 fatty acids, or other antioxidants. We keep an eye on medical research, knowing that partners may ask for lycopene variants tailored for clinical or functional food research, with stricter impurity profiles and custom particle sizes.

    We have seen more brands request naturally derived lycopene blends that mimic the composition of fresh tomatoes, interested in claiming “whole fruit” benefits. Collaboration with researchers and regulatory scientists helps align product development with fast-moving consumer interests, particularly as the line between supplements and functional foods continues to blur.

    Looking ahead, the intersection of sustainability, food safety, and consumer marketing will keep influencing demand and production strategies. Our team remains committed to flexible batch sizes, transparent documentation, and direct technical support—responding to what real product developers, QA staff, and end users want. Having built our operations around practical, honest feedback, our understanding of lycopene goes beyond the whitepapers and market studies—it’s grounded in hands-on experience from tomato field to packaged product.