Sucralose

    • Product Name: Sucralose
    • Chemical Name (IUPAC): 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside
    • CAS No.: 56038-13-2
    • Chemical Formula: C12H19Cl3O8
    • Form/Physical State: White crystalline powder
    • Factroy Site: Lingwu, Yinchuan, Ningxia, China
    • Price Inquiry: sales2@liwei-chem.com
    • Manufacturer: Anhui Liwei Chemical Co.,Limited
    • CONTACT NOW
    Specifications

    HS Code

    485394

    Chemicalname Sucralose
    Iupacname 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside
    Molecularformula C12H19Cl3O8
    Molarmass 397.64 g/mol
    Sweetnessrelativetosucrose About 600 times sweeter
    Physicalappearance White, crystalline powder
    Solubilityinwater Approximately 28.2 g/L at 20°C
    Meltingpoint 125°C (decomposes)
    Caloricvalue Essentially zero (non-caloric)
    Stability Highly stable under heat and over a broad range of pH
    Enumber E955
    Casnumber 56038-13-2

    As an accredited Sucralose factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed plastic container labeled "Sucralose, Net Weight: 1 kg", features chemical formula, batch number, storage instructions, and hazard warnings.
    Container Loading (20′ FCL) Sucralose is loaded in a 20′ FCL using sealed, food-grade drums or cartons, maximizing space while ensuring safety and compliance.
    Shipping Sucralose is shipped in tightly sealed, moisture-resistant containers or bags, typically within sturdy fiber drums or cartons to prevent contamination. It should be stored and transported in a cool, dry environment, away from direct sunlight and incompatible substances. Proper labeling and documentation are required to ensure safe and compliant shipping.
    Storage Sucralose should be stored in a tightly closed container, in a cool, dry, and well-ventilated place, away from direct sunlight, moisture, and incompatible substances. Store at room temperature, avoiding excessive heat. Keep the storage area clean and clearly labeled to prevent contamination and ensure safety in handling. Follow all relevant regulations and safety guidelines for food additives or chemicals.
    Shelf Life Sucralose typically has a shelf life of about 2-3 years when stored in a cool, dry place in sealed containers.
    Application of Sucralose

    Applications of Sucralose in Industrial Manufacturing

    As a global manufacturer of sucralose, we supply high-purity product grades suited for diverse industrial-scale downstream applications, especially in regulated sectors requiring excellent sweetness consistency and process stability. Below we present core application scenarios supported by our technical data, regulatory expertise, and direct collaboration with OEMs and branded goods producers.

    1. Non-Cariogenic Sweeteners for Carbonated Beverage Formulation

    Leading beverage producers incorporate our sucralose for sugar substitution in carbonated and non-carbonated formulations, leveraging its high-temperature resilience during pasteurization and its clean taste profile, which maintains flavor integrity in both diet and mid-calorie soft drinks. Product development relies on regulated ingredient disclosure and strict in-process QC for additive handling during filling and mixing operations, targeting consumer acceptance in markets sensitive to taste and health claims.

    Industry compliance standards

    • GB 2760 (China Food Safety National Standard: Standards for Use of Food Additives)
    • Codex Alimentarius Standard 192-1995 (Food Additive Standard for Sucralose)
    • FDA 21 CFR 172.831 (U.S. Food Additive Permitted Use Regulation)
    • EU Regulation (EC) No 1333/2008 (European Parliament and Council on Food Additives)

    Typical usage ratio

    • Generally 80–180 mg/L (final beverage); dosage adjusted based on total flavor load, acidulant type, and synergy with other high-intensity sweeteners.

    Downstream process integration

    • Addition occurs in syrup blending tanks after filtration, often pre-dissolved for metered dosing, with inline monitoring to ensure compliance with maximum permitted levels before carbonation and bottling.

    Final product types

    • Zero-calorie and reduced-calorie carbonated soft drinks
    • Flavored energy drinks
    • Ready-to-drink iced teas and juice-based sodas

    2. Sugar-Free Chewing Gum and Confectionery

    Industrial gum and confectionery plants implement our sucralose to create long-lasting sugar-free products, optimizing taste retention after extended mastication or dissolving, and minimizing production downtime due to non-hygroscopic handling. Formulators benefit from high recyclability in batch and continuous mixing, while compliance with food safety documentation supports large-scale consumer label requirements and international market entry.

    Industry compliance standards

    • Food Chemicals Codex (FCC) Monograph for Sucralose
    • EFSA Scientific Opinion on the Safety of Sucralose (E 955)
    • Japan Food Sanitation Act Additive List
    • Good Manufacturing Practices (GMP) for Food Industry (e.g. ISO 22000, FSSC 22000)

    Typical usage ratio

    • Approx. 200–400 mg/kg based on total batch weight; higher levels possible in layered/multi-phase products or blends with polyols.

    Downstream process integration

    • Incorporate during dry ingredient blending; for extruded gum—add directly into the mixer; for deposited candy—introduce after syrup cooling, prior to flavoring and molding.

    Final product types

    • Sugar-free chewing gum (pellet, stick, dragee)
    • Hard and soft sugar-free candies
    • Sugarless mint tablets and compressed lozenges

    3. Tabletop Sweetener Compaction and Sachet Packaging

    Producers of retail sweetener products and foodservice sachets depend on sucralose for tablets, powders, and granular blends, owing to its stability under compression, rapid dissolution in hot and cold beverages, and low dusting during automated sachet filling. The material’s compliance with pharmaceutical and food additive pharmacopeias assures finished goods can be marketed under strict labelling and traceability regimes, supporting global distribution and private-label programs.

    Industry compliance standards

    • United States Pharmacopeia (USP)
    • British Pharmacopoeia (BP)
    • ISO 22000 Food Safety Management Standard
    • Health Canada List of Permitted Sweeteners

    Typical usage ratio

    • 8–15 mg/tablet or sachet, typically blended with bulking agents; dosage determined by targeted equivalence to standard sucrose serving size (5g table sugar).

    Downstream process integration

    • Dissolve or dry mix with excipients, followed by tableting via rotary presses or fill-form-seal sachet lines; includes sieving and in-line CCD rejection for particle uniformity.

    Final product types

    • Single-serve retail sweetener sachets
    • Tablets for direct beverage addition
    • Bulk sweetener jars for foodservice and vending applications

    4. Dairy Alternatives and Flavored Milk Processing

    Plant-based beverage and dairy plants choose sucralose to deliver stable sweetness in UHT, ESL, and refrigerated flavored milks, as well as oat, soy, and almond drinks intended for calorie-reduced claims. Its non-fermentable characteristics help mitigate post-pack flavor shift, enabling shelf-stable finishes and product labeling meeting global regulatory demands for low- and no-sugar statements. Technical support ensures precise blending with stabilizer and emulsifier systems during high-shear and thermal steps.

    Industry compliance standards

    • EU Regulation (EU) No 231/2012 (Purity Criteria)
    • FDA GRAS Notice No. 000498 for Dairy Applications
    • CAN/CGSB-32.310 (Canadian Organic Production System – Non-Sugar Sweeteners)
    • Food Sanitation Law of Korea - Schedule of Food Additives

    Typical usage ratio

    • 18–50 mg/L in finished product; fine-tuned via sensory panels and stability testing across various fill-and-pack systems.

    Downstream process integration

    • Add just before homogenization, in pre-heated water or base mix, to ensure complete dissolution prior to UHT or pasteurization; post-heat fill for ready-to-drink formats, with in-process verification against standardized taste specifications.

    Final product types

    • Flavored ultra-high temperature (UHT) milks
    • Plant-based milk alternatives (oat, soy, almond)
    • Meal replacement beverages enriched with vitamins

    5. Oral Pharmaceutical Liquids and Medicinal Syrups

    Pharmaceutical manufacturers utilize our sucralose grades in oral liquid medications and pediatric syrups where sugar-free and tooth-friendly properties are necessary. Direct process compatibility with prescription and OTC suspension base systems supports accurate dosing and stability without color or off-taste interference. We maintain traceable GMP batch records and offer detailed impurity profiles to support regulatory submissions and finished drug release in major healthcare markets.

    Industry compliance standards

    • USP–NF (United States Pharmacopeia–National Formulary) Monograph
    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • Pharmacopoeia Europaea (Ph. Eur.)
    • EMA and FDA Excipients Guidelines for Pharmaceutical Use

    Typical usage ratio

    • 0.15–0.5% w/v; always determined by required palatability and the active pharmaceutical ingredients’ solubility and bitterness profile.

    Downstream process integration

    • Blend into pre-formulated liquid phase under agitation, prior to addition of active drug, ensuring homogeneity before filtration and sterile filling into unit-dose or multi-dose containers.

    Final product types

    • Sugar-free antitussive and expectorant syrups
    • Pediatric oral antibiotic suspensions
    • Fortified vitamin syrups for clinical and at-home administration

    6. Protein Bar and Nutraceutical Product Manufacturing

    Functional food and dietary supplement manufacturers select sucralose for protein bars, meal replacements, and low-carb snacks to achieve consumer-preferred sweetness and calorie targets without Maillard reaction risk or shelf-life constraints associated with reducing sugars. Consistent quality and free-flowing characteristics support high-output bar forming, cold extrusion, and enrobing processes involving a variety of protein and fiber systems targeting athletic and health-conscious markets.

    Industry compliance standards

    • FDA 21 CFR 101.60 (Nutrition Labeling of Sugars and Sweeteners)
    • NOVEL FOOD Regulation (EU) 2015/2283 for Functional Ingredients
    • China GB 29924 (National Standard for Protein Foods)
    • FSSC 22000 Food Safety Certification for Supplement Facilities

    Typical usage ratio

    • 100–330 mg/kg depending on protein, fiber, and fat matrix; typically calibrated against benchmark bar formulations and target consumer taste profiles.

    Downstream process integration

    • Integrate into dry mix together with whey, soy, or plant protein base; suitable for pre-blend with glycerol or polyols before batch cooking, shaping, or cold pressing; post-formulation QC ensures taste uniformity batch-to-batch.

    Final product types

    • High-protein meal replacement bars
    • Keto-friendly snacks and bites
    • Fortified nutrition powders for athletic use

    Free Quote

    Competitive Sucralose prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615380400285 or mail to sales2@liwei-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615380400285

    Email: sales2@liwei-chem.com

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    Certification & Compliance
    More Introduction

    Sucralose: Precision Sweetening from a Manufacturer’s Perspective

    A Look into What Sets Sucralose Apart

    Sucralose stands out in the sweetener world for one simple reason: science has created a molecule that can handle what most sweeteners cannot. Out in the field, companies and manufacturers need something that answers tough questions: Can this additive hold up in heat? Does it leave an aftertaste? Sucralose has become a staple for beverage makers, bakers, pharmaceuticals, and many more, because it quietly solves so many of those problems without fuss.

    Manufacturing sucralose demands deep technical know-how. We don’t just mix up ingredients and send them out the door. The process starts with high-purity sucrose. By selectively replacing three specific hydroxyl groups with chlorine atoms, chemists create a compound that isn’t just hundreds of times sweeter than sugar but stays stable under heat and in storage for months or even years. The structure prevents it from breaking down in the body, which means it contributes no calories.

    From production line to final packaging, every batch needs close attention. The fine white crystalline powder should flow easily, resist clumping, and dissolve quickly. Granulation matters for certain users—drink manufacturers often want an ultra-fine grade that slips seamlessly into solution, while food service companies usually look for a dust-reduced form that won’t cloud the air. Our technical team controls particle size, moisture, and purity to keep these customers satisfied time after time.

    Model and Specifications: What Makes Our Sucralose Reliable

    The best sucralose isn’t just “sucralose.” It’s a carefully engineered chemical product where every specification makes a difference to someone’s line. Our F300 and F400 series each offer slight differences in mesh size and flow, built for specific applications. The F300 model, with its consistent fine-mesh grade, dissolves almost instantly even in cold water, making it ideal for soft drink syrups and dairy products. The F400 series comes as an agglomerated powder, which stays dust-free for easier handling and measures more like table sugar—crucial for bakeries or stick-pack manufacturers.

    Purity always stays above 98%, with chlorinated by-products strictly limited by rigorous chemical analysis. Every kilogram ships after thorough HPLC and conductivity testing. Actual numbers matter—impurity levels below 0.5%, moisture at less than 2.0%—and the difference shows not only in lab reports but right there on our customers’ filling lines. Add sucralose with these specs and you get a product that behaves as it should, each and every time.

    How Sucralose Fits into Real-World Production

    We’ve seen sweetener failures firsthand. Brew a batch of canned iced tea using a typical aspartame formula and that first taste test can turn into a disappointment: sweetness falls apart in days, or temperatures above 80°C destroy the flavor. Sucralose sidesteps these issues. Professional food engineers keep coming back for the stability—pasteurization, sterilization, even baking over 200°C, sucralose stays sweet and leaves no bitter notes or aroma behind. It opens up new formulations: zero-sugar pancake syrups, clear sports drinks, chewable medicines, and all sorts of reduced-calorie snacks.

    For industrial drink lines, our sucralose eliminates production snags. It dissolves on the fly in both batch tanks and continuous blends. No extra steps, no undissolved grit. In bakery production, structurally resilient formulations hold up in rich batters and don’t throw off the crumb, even under prolonged baking cycles. In pharmaceuticals, chemists choose sucralose for syrups and chewable tablets because the chemical stability gives longer shelf life and handles a wide variety of active ingredients without complex interactions.

    Differences Between Sucralose and Other Sweeteners

    Many new entrants still view all sweeteners as variations on a theme, but from inside the factory, distinctions become obvious. While sucralose comes from sugar, it shares very little with table sugar in metabolism or behavior. Saccharin is much older—cheap, long established, and bitter at high dosages. Cyclamate lost market share as health debates lingered, so usage has trended down. Aspartame enjoys broad use, but heat and pH changes often break it down, costing expensive downtime and recalls.

    Stevia and monk fruit both ride waves of “natural” claims, and we’ve processed countless test samples next to sucralose. Compared to stevia, sucralose brings a clean, pure sucrose-like sweetness, without metallic notes, licorice aftertaste, or batch-to-batch variation. Monk fruit extracts sometimes taste pleasant, but purity and cost issues dog the supply chain. In tough technical environments—high-acid sodas, retort-canned products, gummy candies—stevia or monk fruit just don’t last as reliably.

    Maltitol and erythritol, popular as polyol sweeteners, provide bulk but can throw off texture unless you carefully control all parameters. Sucralose, by contrast, packs all its sweetness in a tiny dose—300 to 600 times as sweet as sugar—so food chemists can reformulate products with lower cost, fewer bulking agents, and simpler ingredient lists. For manufacturers running high-speed lines and aiming for both taste and shelf stability, the consistency and predictability save time and money.

    What the Manufacturing Process Teaches

    Years of producing sucralose have taught us that consistency does not happen by accident. Each step from chlorination, through neutralization and purification, creates possible points for contamination or off-flavors. Every ounce of waste, every bit of byproduct, must be treated precisely to avoid safety risks or environmental headaches. Upgrading filtration systems, optimizing reactors, shifting reaction temperatures by a handful of degrees—these little details deliver major benefits.

    Operators must know their reactors and drying equipment inside and out. Experience in scaling up makes all the difference between a robust, repeatable process and a “batch lottery” where no two runs ever match. Storage conditions matter: prevent caking by tightly controlling humidity, pick packaging films that repel moisture and block UV, and work through how the product flows on mixing lines. In our facility, every kilogram tells us about our process health.

    Serving Different Markets with a Single Product

    It might seem easy to make a product that everyone wants to use—at least on paper. In reality, regulatory barriers, technical requirements, and customer habits change with every industry. In beverage and dairy, buyers demand kosher or halal certificates and want sucralose that dissolves quickly without sediment. In the EU and US, regulatory standards on trace impurities differ, especially chlorinated byproducts, so batch logs and testing reports must be bulletproof.

    Foodservice suppliers often care about hygiene and safe handling. One bakery chain we work with wanted a specific anti-caking agent added to the sucralose, all certified to food grade and listed openly. Pharmaceutical buyers ask for even tighter impurity controls and certificates of analysis for every shipment. That means not only investing in higher-purity raw materials, but also keeping meticulous analytical records and responding quickly if a single batch falls out of spec.

    Cosmetics manufacturers take a different angle, sometimes using sucralose to improve taste profile in toothpaste or mouthwash. The importance of clean handling and odor control rises even higher. In all these cases, the basic chemistry stays the same, but the surrounding documentation, testing, and logistics become just as crucial as the molecule itself.

    Why Quality Control Never Ends

    Every chemical process has failure points, and sucralose production is no exception. Minute changes in reaction time, temperature, or input quality can affect not only taste and color, but even consumer safety. Routine batch testing—with GC-MS, HPLC, and spectroscopic checks—catches issues before they reach final packaging. Rejecting a batch stings when it happens, but sending a subpar product without catching errors creates larger headaches down the line, from product recalls to regulatory fines.

    We see a difference in how users respond to high-purity, low-residue sucralose. Suppliers who cut steps or source from questionable intermediates face downstream complaints about taste drift, texture issues, or reactivity with other ingredients. In contrast, running everything in-house and building traceability guarantees that every outgoing lot tracks back to input materials, production day, and QC results. This is not a marketing claim but a necessity to meet both regulatory requirements and the high standards set by consumer brands.

    Efficiency and Sustainability in Modern Sucralose Manufacturing

    Many outsiders don’t realize how much energy and water traditional chemical processes can consume. Years ago, waste management in sucralose plants lagged behind modern expectations, but today’s market punishes inefficiency. Through process improvements, reclaiming solvents, and refining chlorination yields, we cut down on both chemical waste and energy use. Even small shifts—a boost in filtration efficiency, optimizing water usage, or swapping cleaning agents—increase throughput while reducing footprint.

    Dealing with chlorinated waste streams and byproducts isn’t optional. Local regulations specify exact limits for discharge, and we meet or beat those numbers. Many brands now demand third-party environmental audits, pushing our teams to eliminate leaks, improve containment, and recycle as much as feasible. What used to be billed as “waste” now often gets recaptured, cleaned, and returned to the first steps of production. Sucralose, made right, leaves a far lighter mark than it did a decade ago. These upgrades aren’t just for show—they reflect a real shift in industry culture and daily practices.

    The Market’s Evolving Needs and Industry Trust

    Not long ago, the main buyers of sucralose were global beverage giants and a handful of large-scale food producers. The landscape shifted as more mid-sized manufacturers entered performance nutrition, plant-based products, and ready-to-go meal solutions. Each sector brings its own pressures: transparent labeling, “clean” ingredient lists, and verifiable production footprints. Today, the truth behind an ingredient means more than promises on a spec sheet. Buyers check for traceability, test results, and real evidence of safety and reliability.

    We’ve watched audit demands increase, including full supply-chain documentation and closer tracking of input chemicals. Some of our clients run their own random sample checks, and a single off-test batch can ruin years of trust. We see newer food tech firms running small-scale trial runs as they scale up—from initial pilot tests to full launches. They care just as much about consistent sweetness profile as about regulatory letters and clean documentation. That feedback loop with customers keeps quality culture alive from the ground up.

    Problem Solving: Meeting Challenges from Lab to Production

    No two clients use sucralose the same way, so a flexible approach is essential. We’ve worked through scale-up issues with startup beverage blenders, adjusting mesh size to solve uniform mixing in high-speed filling lines. Pharmaceutical formulators sometimes face interactions with excipients, prompting new purity protocols or packaging upgrades. Sometimes performance depends not just on product, but on how users handle it—whether they store it open or sealed, dry or humid, in bulk or repackage.

    Our technical support handles on-site and remote troubleshooting, walking through how to solve issues tied to process water, pH swings, or blending mechanics. Tests in the manufacturer’s own plant often reveal hidden variables—tank cleanliness, agitation strength, or interaction with flavor modifiers. Our team collaborates to tweak specifications, improve handling guides, and even recommend packaging materials. That back-and-forth identifies process changes that prevent the same problem in future batches, not just patching over symptoms.

    In one recent case, a confectionery producer struggled with uneven dispersion in a new gummy product. Site evaluation, side-by-side with the R&D team, tracked the issue down to binder/polyol incompatibility, not sucralose purity. Solution: adjust binder and invest in additional pre-mixing steps. Repairing the application chain means fewer headaches, even if the root cause lies outside our factory.

    Export, Regulation, and Compliance Realities

    Exporting food-grade and pharma-grade sucralose means coping with customs barriers, changing documentation demands, and divergent standards. The US, EU, Middle East, and Asia all keep updating accepted purity thresholds, contamination checks, and label claims. Some markets demand new certificates every year, others every batch. Compliance is never a box to check once—every change in law or regulation affects everything downstream, including labeling, batch release, and in some cases, formula adaptation.

    We’ve had to invest in regulatory staff who track legislation, translate regulatory language, and make sure our documentation matches destination country requirements. Customers trust us to anticipate import questions—sending the right safety data, shipping documents, and ingredient lists up-front so that shipments clear or distributions avoid last-minute registration delays. Quality, safety, and packaging all travel together. If one piece gets overlooked, the time and financial cost can swamp an entire shipment or even a customer’s product launch. We keep learning with every new border, making sure our sucralose supports—not threatens—customer value all around the world.

    Building Trust Through Skill and Experience

    As a manufacturer, every step taken in the production and supply chain builds—or breaks—trust. Decades spent in chemical manufacturing teach us that those who cut corners, hide test results, or swap supplies inevitably stumble as customers raise their own standards. Repeat customers rely on a proven track record. Newcomers test our sucralose in small pilot runs before scaling, trusting laboratory reports and reputation before integrating the product into their business.

    Building that trust happens batch by batch. Every piece of feedback, every audit, and every regulatory inspection provides a chance to learn and upgrade. Chemistry skills, hands-on troubleshooting, an eye for detail—these go further than slogans or low prices. Each successful application, from a new lemonade product line to a reformulated medicine, validates the effort spent on quality and genuine technical support. Our engineers and QA staff see their work reflected every time our material ends up on a new supermarket shelf or in an updated pharmaceutical guide.

    Future Directions in Sucralose Manufacturing

    Demand for reliable, stable, and safe sugar alternatives keeps growing worldwide. Emerging trends in health focus, low-calorie diets, and “sugar taxes” point customers toward sweeteners that work without compromise. Sucralose continues to answer these challenges as a backbone ingredient in a host of evolving industries. We respond by pushing improvements: cleaner reactions, greener methods, longer traceability chains, and even smarter automation on the plant floor.

    Today’s factory floor teams must blend hands-on chemical skills with digital tools for monitoring, data logging, and trace analysis. We’ve invested heavily in these upgrades because a single overlooked deviation can cost customers days—or even trigger a recall. Beyond technology, the heart of a strong sucralose program stays with well-trained staff, institutional experience, and a culture of “test, check, verify.” Satisfying modern demand requires more than chemical formulas: it requires resilience, adaptability, and an ongoing conversation with customers and regulators.

    The Value of Manufacturing Experience

    From production to delivery, making sucralose means combining chemistry, logistics, technical service, and regulatory acumen. We see how seemingly small process decisions become crucial as finished products land on store shelves, in prescription formulas, or behind soda fountains. Our team knows the importance of every test, every shift record, and every question asked by end users, because these moments keep the supply chain running and quality protected.

    Nothing replaces expertise on the shop floor. Our teams don’t just memorize procedures—they understand why each parameter matters, how to pivot during a supply shortage, and how to solve customer challenges wherever they arise. The proof is in the consistency batch after batch, the absence of complaints, and real customer loyalty earned bottle by bottle, tablet by tablet.

    Sucralose is more than an ingredient; for us, it’s an opportunity to demonstrate what focused, detail-driven manufacturing can achieve. This approach keeps us competitive, helps customers develop new products, and ensures every kilogram we ship earns its place in leading brands around the world.